An Unusual Human Mosaic for Skin Pigmentation
- 25 June 1964
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 270 (26) , 1384-1389
- https://doi.org/10.1056/nejm196406252702603
Abstract
AMONG living things, mosaicism has come to mean the mixture in one organism of two or more genetically unlike cell lines. This difference may involve single genes, groups of genes or entire chromosomes. The location and extent of involvement with mosaic traits may hint at the developmental period when the aberrant cell lines arose.The degree of overt mosaicism is not necessarily consistent with the amount of genetic dissimilarity. Some mosaics that show no obvious cellular variance may be distinguished by chromosome analysis whereas others, easily seen, may be impossible to verify by the technics now available.In this paper . . .Keywords
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