A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides
- 1 April 1988
- journal article
- Published by Springer Nature in Nature
- Vol. 332 (6167) , 800-805
- https://doi.org/10.1038/332800a0
Abstract
Depletion of a subset of 70K stress proteins in yeast mutants shows that they are involved in the post-translational import of precursor polypeptides into both mitochondria and the lumen of the endoplasmic reticulum. The identification of such a basic function may explain the remarkable evolutionary conservation of the gene family encoding these proteins.Keywords
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