Inorganic salt modulation of the aqueous solubility of β-cyclodextrin
- 1 July 1993
- journal article
- research article
- Published by Taylor & Francis in Supramolecular Chemistry
- Vol. 2 (2-3) , 93-97
- https://doi.org/10.1080/10610279308038302
Abstract
The effect of mono-, di- and trivalent metal salts on the maximum aqueous solubility of β-cyclodextrin (β-CD) has been investigated. The results show the solubility to be highly dependent on the cation charge: M+ < M2+ < M3+. For chloride as the anion, the solubility increases down Group II for a given salt concentration: Mg2+ < Ca2+ < Sr2+ < Ba2+. However for nitrate as the anion, solubility is largely cation-independent. The increased solubility allows mediumfield NMR (200 MHz) to be used in the study of the β-CD-thymol inclusion complex.Keywords
This publication has 6 references indexed in Scilit:
- Solubility behavior of .beta.-cyclodextrin in water/cosolvent mixturesAnalytical Chemistry, 1992
- Aggregation of cyclodextrins: An explanation of the abnormal solubility of?-cyclodextrinJournal of inclusion phenomena and molecular recognition in chemistry, 1992
- Structure of a .beta.-cyclodextrin-vanillin inclusion complexJournal of Agricultural and Food Chemistry, 1990
- Complex formation of inorganic salts with?-cyclodextrinJournal of inclusion phenomena and molecular recognition in chemistry, 1989
- Solubilization of cyclodextrins for analytical applicationsAnalytical Chemistry, 1989
- Proton NMR study of the inclusion of aromatic molecules in .alpha.-cyclodextrinJournal of the American Chemical Society, 1977