In vitro effect of a glycopeptide acting in vivo on hepatocyte cell cycle
- 1 September 1987
- journal article
- research article
- Published by Wiley in Cell Proliferation
- Vol. 20 (5) , 493-497
- https://doi.org/10.1111/j.1365-2184.1987.tb01358.x
Abstract
A factor specifically inhibiting the hepatocyte cell cycle in vivo was found to block the G1-S transition of liver cells in vitro. It proved to be non-toxic in our culture conditions, as judged by the reversibility of the effect on cell proliferation. It was not active on DNA synthesis in fibroblastic cell lines (3T3).Keywords
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