Normal distribution of acetylation phenotypes in systemic lupus erythematosus
Open Access
- 28 February 1978
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 21 (2) , 192-195
- https://doi.org/10.1002/art.1780210203
Abstract
Previous reports have indicated that idiopathic systemic lupus erythematosus (SLE), like drug‐induced lupus, is more frequent in “slow” hepatic acetylators. Using dapsone acetylation rate to determine phenotypes, we found that of the 18 SLE patients studied, 9 were fast acetylators, 8 were slow, and 1 was indeterminate. This result (53% fast) is similar to acetylator phenotypes in our normal controls (50% fast) and in the population at large (52%).This publication has 5 references indexed in Scilit:
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