Preclinical studies of dynamic treatment modes in pion therapy

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Abstract
Preliminary results on a system for delivering dynamic pion radiotherapy treatments [to cancer patients] are reported. The desired treatment volume is scanned across a small, focused pion beam using a computer-controlled treatment couch. A computer-controlled rangeshifting device modulates the stopping pion depth distribution in coordination with the couch motion to conform the dose to the shape of the treatment volume. For certain shaped tumors the system can result in substantial normal tissue dose sparing and better field flatness as compared to irradiation by static treatments with broad beams. The characteristics of this new system and preliminary results for typical dose distributions as measured with thermoluminescent dosimeters (TLDs) are presented.
Funding Information
  • U.S. Public Health Service (CA14052)
  • U.S. Department of Energy

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