Heart Rate Recovery and Treadmill Exercise Score as Predictors of Mortality in Patients Referred for Exercise ECG

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Abstract
Attenuated heart rate recovery after exercise, which is thought to be a marker of reduced parasympathetic activity,1,2 has been shown to be an independent predictor of mortality among patients referred for stress nuclear testing3 and among healthy adults enrolled in a population-based cohort study.4 The Duke treadmill exercise score, a composite of measures of functional capacity and stress-induced ischemia, has been shown to predict mortality risk in different patient subsets.5-7 It is unknown, however, whether or how heart rate recovery and the treadmill exercise score relate to each other as prognostic measures. The purpose of this study was to determine whether heart rate recovery adds to or interacts with the treadmill exercise score as a predictor of all-cause mortality8 among patients referred for exercise electrocardiography (ECG).

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