A positive difference in nature of envelopes of thymus- and uterus-derived leukemia viruses of AKR mice

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Abstract
Thymus-derived leukemia vims of AKR/J mice was inactivated by anti-theta antiserum. But it was not inactivated by the antiserum which had been absorbed with intact thymus cells of AKR/J or RF/J mice, and by anti-uterus-derived leukemia virus antiserum. In contrast, uterus-derived leukemia virus of the strain was not inactivated by anti-theta antiserum, but was neutralized by anti-uterus-derived leukemia virus antiserum.The results suggest the possibility that some constituents of the envelope of thymus-derived leukemia virus are derived from the plasma membrane of thymus cells of AKR mice at the time of budding and that such constituents are not associated with the envelope of uterus-derived leukemia virus.