Synthesis and biological evaluation of 5‐(1‐alkoxy‐2‐haloethyl)‐2′‐deoxyuridines and related uracil analogues
- 1 February 1991
- journal article
- research article
- Published by Wiley in Journal of Heterocyclic Chemistry
- Vol. 28 (2) , 237-240
- https://doi.org/10.1002/jhet.5570280206
Abstract
A new class of 5‐[1‐alkoxy‐2‐iodo(or 2,2‐diiodo)ethyl] derivatives of 2′‐deoxyuridine and uracil were synthesized by a regiospecific reaction of the C‐5 vinyl substituent with iodine monochloride and an alcohol. These compounds were either weak or inactive antiviral and inactive cytotoxic agents.Keywords
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