A Rapid and Sensitive Method for the Determination of Paraquat in Plasma and Urine by Thin-Layer Chromatography with Flame Ionization Detection
- 29 February 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Analytical Toxicology
- Vol. 12 (2) , 80-83
- https://doi.org/10.1093/jat/12.2.80
Abstract
A new method for the determination of paraquat in biological fluids has been developed. It involves thin-layer chromatography with flame ionization detection (TLC/FID) and simple solid-phase extraction with a disposable octadecylsilane column. This procedure allows direct loading of the samples on the disposable column. When Chromarod SII is used as the stationary phase and methanol-2N hydrochloric acid (2:3, v/v) as the mobile phase, recovery levels of paraquat in spiked materials are from 87.5 to 98.0%. This method can be used for samples of paraquat at levels as low as 50 ng.This publication has 8 references indexed in Scilit:
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