Studies on the asymmetrically attached oligosaccharide of rabbit immunoglobulin-G. I. Biosynthesis and stability of the C2-oligosaccharide.

  • 1 May 1970
    • journal article
    • Vol. 18  (5) , 759-67
Abstract
Two populations of IgG molecules have been isolated from rabbit serum: Type 1, which is devoid of C2-oligosaccharide, and Type II, which has the C2-oligosaccharide attached to only one of the H-chains (Fanger & Smyth, 1970b). By labelling with different isotopes, it was possible to study the stability of the two IgG Types in vitro and in vivo; conclusions could then be drawn concerning biosynthesis of the carbohydrate moiety.