METHODS AND RESULTS OF EXPERIMENTS ON THE EFFECTS OF DRUGS ON BIRD MALARIA*

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Abstract
This paper records the results of attempts to find new therapeutic agents of value in the treatment of malaria. The organism used was Plasmodium praecox, and the experimental animals were canary birds. It was assumed that a compound to be effective must penetrate the red cell in which the parasite is located and that a compound effective against malaria in birds would probably be effective against human malaria also. Drugs belonging to 6 series were tested. Eight drugs among the quinine series were effective against the plasmodia of bird malaria. Several drugs in the other series apparently had a slight effect on bird malaria. Of these, mercurophen seemed the most promising. Work with this drug and other drugs is being continued.
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