Event-related Potentials to Intranasal Trigeminal Stimuli Change in Relation to Stimulus Concentration and Stimulus Duration
- 1 February 2003
- journal article
- clinical trial
- Published by Wolters Kluwer Health in Journal Of Clinical Neurophysiology
- Vol. 20 (1) , 80-86
- https://doi.org/10.1097/00004691-200302000-00011
Abstract
Few data are available on the relation of EEG-derived trigeminal event-related potentials (ERPs) to stimulus duration or stimulus concentration. Thus, the aim of this study was to analyze the relation between ERP components and both stimulus duration and stimulus concentration. Twenty healthy young subjects participated. Trigeminal ERPs were recorded after stimulation with CO2. Five concentrations (45 to 65% volume per volume CO2) and five stimulus durations (100 to 300 msec) were used. Trigeminal ERPs were quantified in terms of amplitudes and latencies of its major peaks N410 (termed N1) and P622 (termed P3). The relation between stimulus duration, concentration, and amplitudes or latencies of trigeminal ERP components could be described as a model of power, following the formula p = b + k · Ig1 ·Dg2 . A linear relationship was found between stimulus concentration, amplitude N1, and amplitude P3, and between stimulus duration and amplitude P3 respectively. Furthermore, a linear relationship was seen between intensity ratings, and stimulus duration and concentration. These data confirm that the different ERP components encode different stimulus characteristics. Specifically, later components of the trigeminal ERP encode not only stimulus concentration but, other than earlier ERP components, also encode stimulus duration. Thus, they reflect the integration of stimuli over relatively long periods of time.Keywords
This publication has 16 references indexed in Scilit:
- Assessment of intranasal trigeminal functionInternational Journal of Psychophysiology, 2000
- Normal aging and odor intensity effects on the olfactory event-related potentialInternational Journal of Psychophysiology, 1999
- Time-Intensity Trading in the Late Auditory Evoked PotentialJournal of Speech, Language, and Hearing Research, 1999
- Chemosensory event-related potentials to trigeminal stimuli change in relation to the interval between repetitive stimulation of the nasal mucosaEuropean Archives of Oto-Rhino-Laryngology, 1999
- Olfactory and intranasal trigeminal event‐related potentials in anosmic patientsThe Laryngoscope, 1998
- ‘Sniffin’ Sticks': Olfactory Performance Assessed by the Combined Testing of Odour Identification, Odor Discrimination and Olfactory ThresholdChemical Senses, 1997
- Psychophysical examination of pain induced by defined CO2 pulses applied to the nasal mucosaPain, 1992
- Temporal integration of pungencyChemical Senses, 1984
- Interaction between chemoreceptive modalities of odour and irritationNature, 1980
- CONTRIBUTION OF THE TRIGEMINAL NERVE TO PERCEIVED ODOR MAGNITUDE*Annals of the New York Academy of Sciences, 1974