Bacterial-Viral Interrelations in Respiratory Infections of Children

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Abstract
CLASSICALLY, one episode of respiratory infection is considered to be produced by one etiologic agent1 2 3 4 5; occasionally, however, multiple infectious agents have been recovered from patients with respiratory illness, suggesting a more complicated pathogenesis.6 7 8 9 10 The frequent occurrence of staphylococcal pneumonia during epidemic influenza has been reported on several occasions,11 , 12 and in some cases, apparent synergism between viruses and bacteria has been noted.13 14 15 16 17 18 19 20 21 MacLeod18 has called attention to the importance of a previous viral infection in the pathogenesis of pneumococcal illness. Recent studies observed significant growth of pathogenic bacteria in throat cultures from patients with rhinovirus infections.6 The present report compares . . .