STUDIES ON EMMONSIELLA CAPSULATA (HISTOPLASMA CAPSULATUM): II. DISTRIBUTION OF THE TWO MATING TYPES IN 13 ENDEMIC STATES OF THE UNITED STATES

Abstract
The distribution of the two mating types in soil and among isolates from human infection was studied. Nine hundred thirty-nine soil isolates and 184 clinical isolates obtained from 13 states in which the organism is endemic were tested for their mating types. The ratio of + and –types among soil isolates was 1: 1, whereas among the clinical isolates there was a 7 (−): 1 (+) ratio. The mycelia of the – type converted to the unicellular form in vitro more readily than the + type.

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