Enantioselective Synthesis of α,α-Difluoro-β-amino Acid and 3,3-Difluoroazetidin-2-one via the Reformatsky-Type Reaction of Ethyl Bromodifluoroacetate with Chiral 1,3-Oxazolidines

This publication has 15 references indexed in Scilit:

• Selective N-dealkylation of tertiary amines derived from phenylglycinol or ephedrine family
  Tetrahedron Letters, 1999
• Enantioselective Biomimetic Transamination of β-Keto Carboxylic Acid Derivatives. An Efficient Asymmetric Synthesis of β-(Fluoroalkyl) β-Amino Acids
  The Journal of Organic Chemistry, 1997
• β‐Peptides: Oligo‐β‐homoalanines – the Amide Analogues of Poly(3‐hydroxybutanoate)
  European Journal of Organic Chemistry, 1997
• Inhibition of human leukocyte elastase by functionalized N-aryl-3,3-dihalogenoazetidin-2-ones. Stereospecific synthesis and chiral recognition of dissymmetrically C3-substituted β-lactams
  Tetrahedron: Asymmetry, 1997
• Stereocontrolled synthesis of chiral secondary (α-methylene-β-substituted)-γ-lactams by addition of β-functional crotylzinc reagents to chiral imines
  Tetrahedron: Asymmetry, 1996
• An efficient enantiomeric three step synthesis of β-amino acids (esters)
  Tetrahedron Letters, 1993
• Synthesis of chiral .alpha.-alkyl phenethylamines via organometallic addition to chiral 2-aryl-1,3-oxazolidines
  The Journal of Organic Chemistry, 1991
• Preparation and properties of chiral fluoroorganic compounds
  Tetrahedron: Asymmetry, 1990
• The ester enolate-imine condensation route to .beta.-lactams
  Chemical Reviews, 1989
• Synthesis of 3,3-difluoro-2-azetidinones and 2,3-dideoxy-2,2-difluoro-3-amino-sugars through the reformatsky reaction of difluoroacetate with imine
  Tetrahedron Letters, 1988