Isoelectrofocusing in the Study of the Bf System: Existence of Two Common Subtypes of the Bf^F Allele

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Abstract
The inherited polymorphism of the properdin factor B (Bf system) was studied by isoelectrofocusing in polyacrylamide gel (PAGIF, pH range 5.0-8.0), followed by immunofixation. Using the described technique, two different subtypes of F bands are visible (designated as F' and F"). Studies of 13 families and 48 mother-child pairs are not in contradiction to the assumption of a codominant inheritance by two alleles (Bf^F' and Bf^F") at a single locus.

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