ASSESSMENT OF SERUM MYOGLOBIN AS A MARKER FOR ACUTE MYOCARDIAL-INFARCTION

  • 1 January 1979
    • journal article
    • research article
    • Vol. 20  (2) , 115-119
Abstract
The reliability of serum myoglobin as a marker for acute myocardial infarction was evaluated in 157 consecutive coronary-care admissions. Admission myoglobin was elevated in 47 of 52 patients with acute infarction. Excluding patients who presented later than 24 h after symptom onset, only 1 patient with acute infarct had a normal admission myoglobin. In 22 of 105 patients with no infarct, myoglobin was elevated in association with angina, congestive heart failure, arrhythmias and renal insufficiency. The detection of acute infarction by serum myoglobin measurement equals that of serial serum creatine phospholinase isoenzymes (CPK-MB) by electrophoresis but an elevated myoglobin is not specific for diagnosis of clinically significant myocardial infarction.