Stabilization of Actin Filaments by ATP and Inorganic Phosphate
Open Access
- 1 August 1989
- journal article
- research article
- Published by Walter de Gruyter GmbH in Zeitschrift für Naturforschung C
- Vol. 44 (7-8) , 698-704
- https://doi.org/10.1515/znc-1989-7-824
Abstract
Both inorganic orthophsophate and ATP stabilize actin filaments. This is reflected by a reduced nucleotide exchange and by a protection against filament breakdown by SDS or KI. When the filament-stabilizing effect of ATP was maximal, only about 25% of the actin subunits of the filament had bound one molecule of the nucleotide offered in the stabilizing solution.Keywords
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