Borderline or malignant ovarian tumour? A case report of decision making with morphometry.

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Abstract
A young woman presented with bilateral ovarian tumors. Multiple sections of each tumor were shown to many pathologists for consultation; some considered the tumors to be borderline, whereas others thought that one or both of them was malignant. Morphometry showed that the numerical classification probabilities for borderline tumor were 0.78 for the left ovarian tumor and 0.85 in the right. The lesions were therefore regarded as borderline tumors and no additional chemotherapy was given. Three years after the 2nd operation the patient is alive and well without clinical or biochemical evidence of recurrence. Most patients with borderline tumors who die from the disease do so in the 1st 2 yr after the operation. This young patient was prevented from severe overtreatment by the application of morphometry, illustrating its use in this area of diagnostic gynecopathology.