T-CELL LYMPHOMA AND THE CHEDIAK-HIGASHI-SYNDROME

  • 1 January 1982
    • journal article
    • research article
    • Vol. 60  (3) , 672-676
Abstract
The majority of patients with Chediak-Higashi syndrome (CHS) develop a lymphoproliferative disorder during the accelerated phase of the disease. Controversy exists regarding the benign vs. malignant nature of this cellular proliferation. For the 1st time, the immunologic cell markers on the cellular infiltrate were characterized in a lymph node from a patient with CHS. The infiltrate was composed almost entirely of T cells, with histopathologic features consistent with a non-Hodgkin''s T cell lymphoma.