Comparative Studies of Hemoperfusion Devices II. Pressure Drop and Flow Uniformity Tests
- 1 January 1979
- journal article
- research article
- Published by Taylor & Francis in Biomaterials, Medical Devices, and Artificial Organs
- Vol. 7 (3) , 443-454
- https://doi.org/10.3109/10731197909119391
Abstract
The technique of hemoperfusion has recently become an accepted method for treating victims of severe poisonings or drug overdoses. One resin-based hemoperfusion device and 3 charcoal-based hemoperfusion devices were tested to determine their pressure drop and flow uniformity characteristics. Measurements were made on pressure drop vs. flow rate using distilled water and on pressure drop vs. time using bovine blood. Effluent concentration curves obtained after the step-change introduction of a high MW dye solution to each unit were used to determine the priming volumes of the devices and were interpreted to yield information regarding the uniformities of flow in each device. The pressure drop and priming volume values for the resin-based device were significantly higher than the corresponding values for the charcoal-based units.This publication has 3 references indexed in Scilit:
- Biocompatibility of coated and uncoated charcoal during haemoperfusion in healthy dogsEuropean Journal of Clinical Investigation, 1977
- Considerations of Species-Related Hematological Differences on the Evaluation of BiomaterialsBiomaterials, Medical Devices, and Artificial Organs, 1977