Interferon‐Gamma Production by African Swine Fever Virus‐Specific Lymphocytes
- 1 February 1992
- journal article
- Published by Wiley in Scandinavian Journal of Immunology
- Vol. 35 (2) , 225-230
- https://doi.org/10.1111/j.1365-3083.1992.tb02854.x
Abstract
Peripheral blood mononuclear cells (PBMC) from inbred pigs that were immunized with autologous macrophages infected with the African swine fever (ASF) virus BA71V, a non-virulent virus isolate, proliferated and produced interleukin-2 in response to homologous and heterologous isolates of the ASF virus. They produced, however, interferon (IFN) only when challenged in vitro with homologous or attenuated isolates of the ASF virus, but not with heterologous or virulent isolates. The IFN was pH 2 labile and was neutralized by specific serum to porcine recombinant IFN gamma.Keywords
This publication has 18 references indexed in Scilit:
- Dengue virus-specific human T cell clones. Serotype crossreactive proliferation, interferon gamma production, and cytotoxic activity.The Journal of Experimental Medicine, 1989
- Variable and constant regions in african swine fever virus DNAVirology, 1989
- Effect of Interferon- , Interferon- and Tumour Necrosis Factor on African Swine Fever Virus Replication in Porcine Monocytes and MacrophagesJournal of General Virology, 1988
- A colorimetric assay based on cell viability for the indirect detection of intracellular replication and killing of Trypanosoma cruziJournal of Immunological Methods, 1987
- Molecular Biology of African Swine Fever VirusPublished by Springer Nature ,1987
- Cell-mediated immune responses to influenza virus antigens expressed by vaccinia virus recombinantsMicrobial Pathogenesis, 1986
- Production and titration of African swine fever virus in porcine alveolar macrophagesJournal of Virological Methods, 1982
- TRANSPLANTATION IN MINIATURE SWINETransplantation, 1976
- Titration of African Swine Fever (ASF) VirusJournal of General Virology, 1976
- Studies to determine neutralizing antibody in sera from animals recovered from african swine fever and laboratory animals inoculated with african virus with adjuvantsArchiv für die gesamte Virusforschung, 1967