Synthesis of Optically Active Cyanohydrins Using Almond Meal
- 1 June 1991
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 21 (12-13) , 1387-1391
- https://doi.org/10.1080/00397919108021286
Abstract
Asymmetric hydrocyanation of aldehydes was accomplished using almond meal, containing the enzyme oxynitrilase. Optically active cyanohydrins with high levels of enantiomeric purity were obtained following a simple procedure.Keywords
This publication has 10 references indexed in Scilit:
- Transimination. Conversion of nitriles into secondary amines in a one‐pot reactionRecueil des Travaux Chimiques des Pays-Bas, 1991
- Enzyme‐Catalyzed Synthesis of (S)‐CyanohydrinsAngewandte Chemie International Edition in English, 1990
- Synthesis of optically active silyl protected cyanohydrinsTetrahedron, 1990
- Ein einfacher Zugang zu (R)-α-Hydroxycarbonsäuren und (R)- 1-Amino-2-alkoholen aus (R)-CyanhydrinenSynthesis, 1990
- Synthesis of optically active ethanolamines.Tetrahedron, 1989
- Bio-organic synthesis of optically active cyanohydrins and acyloinsTetrahedron Letters, 1988
- The Asymmetric Hydrocyanation of Aldehydes with Cyanotrimethylsilane Promoted by a Chiral Titanium ReagentChemistry Letters, 1987
- Enzyme‐Catalyzed Cyanohydrin Synthesis in Organic SolventsAngewandte Chemie International Edition in English, 1987
- Chiral Lewis acids for enantioselective CC bond formationTetrahedron Letters, 1986
- Asymmetric cyanohydrin synthesis catalysed by a synthetic cyclic dipeptideJournal of the Chemical Society, Chemical Communications, 1981