Physicochemical Aspects of Microencapsulation

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Abstract
Microencapsulation is a process whereby small discrete solid particles or liquid droplets are completely engulfed by an intact membrane. The concept of microencapsulation originated a number of years ago and was initially utilized in carbonless copy papers [1]. More recently, it has received increasing attention in biomedical applications [2] and as a means of packaging Pharmaceuticals for controlled release purposes [3,4]. Both solids and liquids have been encapsulated successfully. Although most microcapsules fall between 5 and 500 μ diameter, they can be made below 1 μ and up to 5000 μ diameter. One can argue whether or not the latter should be classified as microcapsules. The material contained within a microcapsule is called the internal phase (IP) or core material. Because of the author's familiarity with the term IP, it will be used exclusively in this paper.

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