In situ rheological characterization of epithelial mucus1

Abstract
A technique for monitoring rheological characteristics of mucus in situ was described; the technique consists of a fine probe introduced into the epithelium to various depths, simulating the effect of extravenously introduced particles in such a way that the force on the particle or probe can be measured. A complex mathematical relationship was formulated to describe the situation. Measurements were made on frog and toad palate epithelia. A plot of shear stress against shear rate showed typically the flow curve of a non Newtonian fluid with an upper and presumably lower Newtonian region.

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