Sodium-Dependent Interaction of Benzamides with Dopamine Receptors in Rat and Dog Anterior Pituitary Glands
- 1 January 1981
- journal article
- research article
- Published by S. Karger AG in Neuroendocrinology
- Vol. 32 (2) , 103-107
- https://doi.org/10.1159/000123139
Abstract
Sulpiride and other benzamides'' [butaclamol, sultopride, clebopride, tiapride, 2-amino-6,7-dihydroxytetralin, dopamine, serotonin, haloperidol, fluphenazine, apomorphine] displacement of [3H]-spiroperidol binding to rat and dog anterior pituitary dopaminergic receptors was selectively Na dependent, while typical neuroleptic activity was not influenced by NaCl. These results evidently indicate the existence in the anterior pituitary of a subpopulation of dopaminergic receptors with which benzamides interact.This publication has 10 references indexed in Scilit:
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