Syringin 4-O-β-Glucoside, a New Phenylpropanoid Glycoside, and Costunolide, a Nitric Oxide Synthase Inhibitor, from the Stem Bark of Magnolia sieboldii
- 1 January 1996
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 59 (12) , 1128-1130
- https://doi.org/10.1021/np960452i
Abstract
Syringin 4-O-β-glucoside (1), a new phenylpropanoid glycoside, and costunolide (2) were isolated from the stem bark of Magnolia sieboldii. The structures were determined by spectroscopic and chemical methods. Costunolide (2) exhibited strong nitric oxide synthase inhibitory activity in the endotoxin-activated murine macrophage, J774.1.Keywords
This publication has 9 references indexed in Scilit:
- Depressive Effect of a Traditional Chinese Medicine (Sho-Saiko-To) on Endotoxin-Induced Nitric Oxide Formation in Activated Murine Macrophage J774A.1 Cells.Biological & Pharmaceutical Bulletin, 1995
- Bacterial endotoxin rapidly stimulates prolonged endothelium‐dependent vasodilatation in the rat isolated perfused heartBritish Journal of Pharmacology, 1993
- Aristolactams and a 4,5-Dioxoaporphine Derivative fromHouttuynia cordataPlanta Medica, 1992
- (-)-Fargesol, A New Lignan from the Flowers Buds ofMagnolia fargesiiPlanta Medica, 1990
- A diterpene, distanol, from Sideritis distansPhytochemistry, 1989
- Two new phenylpropanoid glycosides from Wikstroemia sikokiana.CHEMICAL & PHARMACEUTICAL BULLETIN, 1988
- Structural Features ofPlantago lanceolata MucilagePlanta Medica, 1985
- Dental Caries Prevention by Traditional Chinese Medicines*Planta Medica, 1982
- 15-Acetoxycostunolide from Magnolia sieboldiiPhytochemistry, 1982