Pseudomonas stutzeri bacteremia associated with hemodialysis

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Abstract
P. stutzeri bacteremia developed in 6 patients undergoing hemodialysis. Fever, shaking chills, nausea and vomiting were observed. All patients recovered, although only 2 received specific antibiotic therapy. The infections occurred sporadically over 9 mo. P. stutzeri was subsequently isolated from the dialysate that circulates within the hemodialysis machine. The ultimate source was the deionized water that is combined with the liquid concentrate to form the dialysate. P. stutzeri was localized to the top cannister of the dialysis machine, but was also isolated throughout the machine, including the bottom reservoir and the recirculating pump. The emphasis on handwashing, strict compliance with disinfection procedures and elimination of prolonged sitting times for the filled machine after disinfection resulted in no further cases of P. stutzeri infection.