Contiguous stereogenic quaternary carbons: A daunting challenge in natural products synthesis
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- 1 July 2004
- journal article
- review article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 101 (33) , 11943-11948
- https://doi.org/10.1073/pnas.0402416101
Abstract
One element of structure that invariably increases the difficulty of a chemical synthesis is the presence in the target molecule of contiguous all-carbon quaternary stereocenters. This Perspective will examine the most useful transformations and strategies devised recently for directly assembling this structural unit.Keywords
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