Rh immune globulin and the Rh‐positive Du variant, mother

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Abstract
Questions have been raised by statements of the American College of Obstetricians and Gynecologists [USA] that Rh immune globulin should be given to all Rh positive, Du variant, [human] mothers who have recently delivered Rh-positive infants. This practice is not recommended. However, blood banks must assure that a positive Du test on a mother''s blood sample is not caused by a massive fetal-maternal hemorrhage. Failure to recognize this cause of a positive Du test may result in the administration of an inadequate dose of Rh immune globulin.