FLOW MICRO-FLUOROMETRIC ANALYSIS OF THE CELL-CYCLE PHASE CYTO-TOXICITY OF ARA-C

  • 1 January 1980
    • journal article
    • research article
    • Vol. 30  (2) , 365-368
Abstract
Mouse L1210 leukemia cells killed by ara-C [cytosine arabinoside], an antitumor agent widely used against leukemia, were demonstrated to be in the S phase of the cell cycle by flow microfluorometry. The point in S phase at which the L1210 cells died was dose-dependent. At higher concentrations of ara-C, cells died earlier in the S phase.

This publication has 0 references indexed in Scilit: