CORRELATION OF BOILING RANGES OF SOME PETROLEUM SOLVENTS WITH IRRITANT ACTION ON SKIN

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Abstract
Physicians dermatitis appearing after contact with petroleum products are handicapped in obtaining information regarding the physical and chemical properties of these products. The wide use of nondescriptive brands and trade names and the heterogeneous nature of petroleum products make it difficult to evaluate their role in causing dermatitis. This was apparent in our studies of patients exposed to a class of petroleum derivatives often referred to as mineral seal oils. Our purpose is to facilitate judgment of the role of petroleum products in causing dermatitis by classifying such products commonly encountered by industrial physicians and to indicate the identifying properties of the various classes. CLASSIFICATION OF PETROLEUM PRODUCTS Petroleum is composed of an intimate mixture of thousands of hydrocarbon compounds, with paraffins (CnH2n+2) and cycloparaffins or naphthenes (CnH2n) predominating and oleofins, acetylenes, aromatics and other cyclic hydrocarbons present in lesser amounts. Sulfur, oxygen and

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