Urinary Excretion of Amino-acids During Alloxan-induced Diabetes in Rats.

Abstract
N balance studies during periods of normal control, of alloxan-induced diabetes with insulin therapy, and of fatal acidosis after withholding insulin, are reported. The pattern of excretion of urinary amino-acids, and the ratio of total amino-acid N to total urinary N remained essentially unchanged throughout the 3 periods, including the terminal stage with its greatly increased loss of total N.