Human Lymphocyte Antigen Reactivity Modified by Neuraminidase
- 6 August 1971
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 173 (3996) , 542-544
- https://doi.org/10.1126/science.173.3996.542
Abstract
Human lymphocytes treated with neuraminidase (from Vibrio cholera) are more susceptible to lysis with antiserums directed against HL-A antigens in the cytotoxicity test than are the corresponding cells incubated in buffer. Enzymetreated cells are also lysed by antibodies other than those directed against HL-A, but control cells are not. The extra sensitivity to antibody disappears after 2 to 6 days in tissue culture.Keywords
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