Atemoyin, A New Bis-Tetrahydrofuran Acetogenin from the Seeds ofAnnona atemoya1

Abstract
A new acetogenin belonging to the rare C35-type bis-tetrahydrofuran acetogenins, atemoyin (1) was isolated from the MeOH extract of Annona atemoya seeds, in addition to the known compounds, neoannonin (2), desacetyluvaricin (3), isodesacetyluvaricin (4), squamocin (5) and rolliniastatin-2 (6). The structure of 1 was elucidated by spectroscopic techniques and confirmed by a chemical method.