Bronchopulmonary Dysplasia and Vitamin E

Abstract
In 1967, examples of acute, subacute and chronic pulmonary disease were described in a series of 32 newborn infants with severe respiratory-distress syndrome, treated for 24 hours or more with warm humidified, 80 to 100 per cent oxygen via an intermittent positive-pressure respirator.1 A picture of a then new syndrome, termed bronchopulmonary dysplasia, was presented. Chest radiographs correlated well with the evolution of the cardiorespiratory disease and showed an acute stage indistinguishable from any severe case of respiratory-distress syndrome in a premature infant and a second stage (four to 10 days), in which almost the whole lung showed mottled, dense . . .