OCULAR INVOLVEMENT IN SYSTEMIC IDIOPATHIC FIBROSIS

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Abstract
Systemic idiopathic fibrosis is a rare disease characterized by a nonsuppurative inflammation of fat and connective tissue in many anatomic sites with subsequent fibrosis and sclerosis of the involved tissue. A 29-year-old patient is presented who manifested bilateral exophthalmos as the first sign of systemic idiopathic fibrosis. The patient subsequently developed fundus changes, including disc edema, retinal hemorrhages, a serous retinal detachment, and retinal pigment epithelial lesions that responded rapidly to oral prednisone therapy. She died shortly thereafter from complications of her disease.

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