Guanine-7-oxide, a novel antitumor antibiotic.

Abstract
A new antibiotic, PD 113,876, was isolated from the culture broth of a Streptomyces sp. and was shown by X-ray diffraction analysis to be the N-7 oxide of guanine. This novel antimetabolite is very active in vivo against L1210 lymphocytic leukemia.

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