Tracing the origin of Brazilian HTLV-1 as determined by analysis of host and viral genes

21 March 2006

journal article
research article
Published by Wolters Kluwer Health in AIDS

Vol. 20 (5) , 780-782
https://doi.org/10.1097/01.aids.0000216383.14808.13

Abstract

We compared the genetic diversity of the Brazilian human T-cell lymphotropic virus type 1 isolates with those found in KwaZulu–Natal (KZN), South Africa, and with the genetic background of the hosts. The seroprevalence rate in KZN was 1.7%. All sequences belonged to the A subgroup. The presence of South African sequences in two different clusters from Brazil, and the finding of the β^A-globin haplotype in infected hosts are consistent with the transmission of this virus from southern Africa to Brazil.

Keywords

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