Virus-like Particles in Bovine Sera for Tissue Culture

Abstract
Virus-like particles were found in 9 different bovine sera for tissue culture from commercial suppliers. These particles were spherical with an overall diameter of 70-95 nm. After negative staining surface projections of .apprx. 11-12 nm were clearly seen. Of the 9 sera, 1 was positive in an Ouchterlony test with antisera against bovine viral diarrhea virus.

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