Loss of Rh Antigen Activity Following the Action of Phospholipase A2 on Red Cell Stroma
- 1 September 1975
- journal article
- Published by Wiley in Vox Sanguinis
- Vol. 29 (3) , 184-191
- https://doi.org/10.1111/j.1423-0410.1975.tb00493.x
Abstract
The degradation of red cell stroma phospholipids by phospholipase A2 is accompanied by a concomitant fall in the activity of the Rh antigens, c, D and e. The action of phospholipase C on stroma also brings about a fall in D antigen activity. Anti-D bound to the red cells protects the D antigen from inactivation by phospholipase A2.Keywords
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