Abstract
The entry of 125I-labelled ovine follicle-stimulating hormone (FSH) and human serum albumin into the seminiferous tubules of rams has been studied by measuring radioactivity in blood plasma and rete testis fluid after an intravenous injection of the labelled protein. After the injection of FSH, radioactivity/mg total protein in rete testis fluid exceeded that in blood plasma from the first day onwards, but after the injection of human serum albumin, radioactivity/mg total protein in rete testis fluid only reached that in plasma after 4–5 days and never exceeded it. Protein-bound radioactivity disappeared from the blood more quickly after an injection of FSH than after an injection of albumin.

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