Cerebrospinal Fluid Concentrations of Somatostatin and Biogenic Amines in Grown Primates Reared by Mothers Exposed to Manipulated Foraging Conditions

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Abstract
THE PIVOTAL role of adverse early life experiences in the pathogenesis of adult psychopathological symptoms has long been recognized in both psychoanalytic circles1 and systematic epidemiologic studies.2,3 Primate infants, human and nonhuman, display a relatively extended period of dependence on their mothers during development. Relatively subtle disruptions during critical "windows" of maternal-infant affective interaction may come to symbolize a threat to survival, with long-term behavioral and biological (mal)adaptions.4

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