A model eliciting transient responses
- 1 January 1984
- journal article
- Published by American Physiological Society in American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- Vol. 246 (1) , R114-R121
- https://doi.org/10.1152/ajpregu.1984.246.1.r114
Abstract
A simple parametrically controlled chemical transformation scheme is used to exemplify a model with transient response to sustained stimulation. More complicated schemes are also discussed. Analyses of three experimental examples are given: short-circuit current changes in toad bladder exposed to adenosine 3',5'-cyclic monophosphate (cAMP) stimulation; histamine secretion in acetylcholine-stimulated frog gastric mucosa; and cAMP dynamics, expressed in terms of adenylate cyclase dynamics, in histamine-stimulated frog gastric mucosa. The model responds primarily to the changes of the stimulator level, although it is not a model with derivative control.Keywords
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