Epoxygenation of arachidonic acid by rat anterior pituitary microsomal fractions
- 10 December 1984
- journal article
- Published by Wiley in FEBS Letters
- Vol. 178 (2) , 319-322
- https://doi.org/10.1016/0014-5793(84)80625-0
Abstract
Microsomal fractions isolated from rat anterior pituitary glands catalyze the oxygenation of arachidonic acid. By a combination of Chromatographic and mass spectrometric techniques, we have identified epoxy‐eicosatrienoic acids as reaction products and thus documented the presence of an NADPH‐dependent arachidonic acid epoxygenase activity in rat adenohypophysis.Keywords
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