Ion Exchange in Reversed-Phase Chromatography of Some Simple Organic Cations

Abstract
Capacity factors of phenylalkylammonium and phenylammonium ions are linearly related to the reciprocal of the mobile phase eluent cation concentration for methanol-water mobile phases on a silica-based octadecyl column. Intercepts of these curves are considered to be capacity factors for pure reversed-phase interaction. Slopes of the curves are used to measure ion exchange tendency. The results indicate that ion exchange is aided by solvophobicity of the eluite.

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