Effects of Adrenaline and Noradrenaline on Euglobulin Lysis Time and Effects of Adrenergic Receptor Blocking Agents on Shortening of Lysis Time by Adrenaline

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Abstract
Adrenaline in an intravenous dose of 0.1 µg per kg induced a significant shortening of the euglobulinlysis time in 8 healthy subjects. On the other hand, the euglobulin lysis time was not hastened by intravenous injections of the same dose of 1-noradrenaline in 8 healthy subjects. The shortening of the euglobulin lysis time induced by 0.1 µg per kg of adrenaline was blocked by the pretreatment with 300 mg of nethalide in 8 healthy subjects but not blocked by the pretreatment with 30 mg of phenoxybenzamine in 5 healthy subjects.