Biotransformation in organic synthesis: applications of yeast reduction in the synthesis of 3,5-dihydroxy esters of high optical purity
- 1 January 1988
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 4,p. 264-266
- https://doi.org/10.1039/c39880000264
Abstract
All four stereoisomers of methyl 6-(p-chlorophenylthio)-3,5-dihydroxyhexanoate have been synthesised by a route in which the key introduction of chirality was effected by an appropriate yeast reduction.Keywords
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