Cyclodepsipeptides from Beauveria bassiana. Part 2. Beauverolides A to F and their relationship to isarolide
- 1 January 1980
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 8,p. 1795-1799
- https://doi.org/10.1039/p19800001795
Abstract
In some fermentations with a Beauveria bassiana strain capable of producing beauverolides A–F, the beauverolide metabolites contain alloisoleucine residues in place of isoleucine and are designated by the subscript a. Beauverolides Ea and Fa are shown to be the cyclotetradepsipeptides cyclo-[3-hydroxy-4-methyloctanoyl-L-valyl-L-phenylalanyl-D-alloisoleucyl] and cyclo-[3-hydroxy-4-methyloctanoyl-L-phenylalanyl-L-phenylalanyl-D-alloisoleucyl] respectively. Beauverolides Ba and Ca are the homologues derived from 3-hydroxy-4-methyldecanoic acid. Beauverolide Ba is identical with Isarolide A and with beauverilide A. Beauverolide Ca is identical with Isarolide C. The structures of beauverolides A and D are deduced from the mass spectra of the beauverolide mixture.This publication has 0 references indexed in Scilit: